The last six SUDS-positive cases received were tested further by the third-generation Abbott HIV1/2 EIA. These samples were received from several Michigan hospital laboratories and represented patients involved in health care worker exposures as well as patients being screened for HIV infection. The retrospective study evaluated the Western blot assay results of 38 consecutive SUDS-positive sera received at our reference laboratory (Ann Arbor, Mich.) from January 1998 through February 1999. The purpose of this two-armed study was to compare the standard enzyme immunoassay (EIA) screen with the SUDS test. The Food and Drug Administration-approved Murex Single-Use Diagnostic System (SUDS Abbott Laboratories), a rapid qualitative immunoassay, is in wide use in our region (lower Michigan). ![]() For example, a rapid HIV status result may be needed for initiating prophylactic therapy after possible HIV exposure ( 1), prior to listing patients for organ transplantation ( 4, 6), and in a public health setting ( 3). Occasionally, the human immunodeficiency virus (HIV) status of an individual is needed urgently.
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